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  • Primary Antibodies ›
  • CNGA1 Antibodies

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CNGA1 Polyclonal Antibody

2 References
View all (6) CNGA1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite CNGA1 Polyclonal Antibody

CNGA1 Polyclonal Antibody

Product Details

OSC00168W-100UL

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-1:2,000
-

Immunohistochemistry (IHC)

1:300-1:2,000
-

Miscellaneous PubMed (MISC)

-
View 2 publications 2 publications
Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from aa region 100-150 of mouse CNGA1 conjugated to an immunogenic carrier protein was used as the antigen
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: CNGA1.

Target Information

The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: cGMP-gated cation channel alpha-1; cng channel; CNG channel alpha-1; CNG-1; CNG1; cyclic nucleotide gated channel, cGMP gated; Cyclic nucleotide-gated cation channel 1; Cyclic nucleotide-gated channel alpha-1; Cyclic nucleotide-gated channel, photoreceptor; Rod photoreceptor cGMP-gated cation channel subunit alpha; rod photoreceptor cGMP-gated channel subunit alpha

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Gene Aliases: Cncg; Cncg1; Cnga1

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UniProt ID: (Mouse) P29974

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Entrez Gene ID: (Mouse) 12788

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Function(s)
nucleotide binding ion channel activity intracellular cAMP activated cation channel activity intracellular cGMP activated cation channel activity voltage-gated potassium channel activity cGMP binding
Process(es)
transport ion transport visual perception regulation of ion transmembrane transport regulation of membrane potential response to stimulus regulation of cytosolic calcium ion concentration membrane depolarization transmembrane transport potassium ion transmembrane transport cation transmembrane transport
It has to be done as per old AB suggested Products section.
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