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Invitrogen
CK1 alpha Monoclonal Antibody (3C10F7, 3C10G5, PMC01, 4D12B3,3C10F7C11)
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Product Details
MA5-15300
Species Reactivity
Host/Isotype
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Type
Clone
Immunogen
Conjugate
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Product Specific Information
MA5-15300 targets CK1 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples.
The MA5-15300 immunogen is purified recombinant fragment of CK1 expressed in E. Coli.
Target Information
CNSK1A1 (CK1 alpha 1) is a member of the casein kinase I (CKI) gene family, which encodes serine/threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric, ranging from 25 to 55 kD, and are found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: casein kinase 1, alpha 1; Casein kinase I isoform alpha; CK I alpha; CK-I alpha; CK1; CKI alpha; CKI-alpha; clock regulator kinase; CSNK1A1/CK1; down-regulated in lung cancer; epididymis secretory sperm binding protein Li 77p; OTTHUMP00000224000; OTTHUMP00000224001; OTTHUMP00000224003; YIL035C
Gene Aliases: CK1; CK1a; CKIa; CSNK1A1; HEL-S-77p; HLCDGP1; PRO2975
UniProt ID: (Human) P48729
Entrez Gene ID: (Human) 1452
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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