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NeoBiotechnologies
CEBPZ Monoclonal Antibody (PCRP-CEBPZ-2D8)
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Product Details
10153-MSM2-P1ABX
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
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Purification
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Product Specific Information
Positive Control:Human skin or placenta. HeLa cells.
Cellular Location: Nucleus.
Target Information
This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurrence of acute myeloid leukemia (AML).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: C EBP; C/EBP zeta; CBF; CCAAT-box-binding transcription factor; CCAAT/enhancer binding protein (C/EBP), zeta; CCAAT/enhancer binding protein cebp family zeta; CCAAT/enhancer-binding protein zeta; CEBP zeta; CTF2; HSPCBF
Gene Aliases: CBF; CBF2; CEBPZ; HSP-CBF; NOC1
UniProt ID: (Human) Q03701
Entrez Gene ID: (Human) 10153
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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