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NeoBiotechnologies
CD6 (Negative Marker of T-regulatory Cells) Monoclonal Antibody (SPV-L14)
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Product Details
923-MSM3-P1ABX
Species Reactivity
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Clone
Immunogen
Conjugate
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Target Information
CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CD6; CD6 antigen; FLJ44171; T-cell differentiation antigen CD6; T12; TP120
Gene Aliases: CD6; TP120
UniProt ID: (Human) P30203, (Mouse) Q61003
Entrez Gene ID: (Human) 923, (Mouse) 12511
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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