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Proteintech
CD1d Monoclonal Antibody (1B1), CoraLite® Plus 647
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FIGURE: 1 / 1
CD1d Antibody (CL647-65242) in Flow
Product Details
CL647-65242
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Excitation/Emission Max
Form
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Target Information
CD1d is a heavy chain associated with Beta 2 microglobulin on cortical thymocytes. Beta 2 microglobulin independent expression of CD1d has also been demonstrated on human intestinal epithelial cells. CD1d is the sole group 2 member of the CD1 family of major histocompatibility (MHC) like glycoproteins. The CD1d gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by the CD1d gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Diseases associated with CD1D include Mycobacterium Malmoense and Autoimmune Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Antigen-presenting glycoprotein CD1d1; CD1d.1; T-cell surface glycoprotein CD1d1
Gene Aliases: AI747460; CD1.1; Cd1a; Cd1d; Cd1d1; Ly-38
UniProt ID: (Mouse) P11609
Entrez Gene ID: (Mouse) 12479
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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