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Invitrogen
CD123 Polyclonal Antibody
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Product Details
PA5-82102
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Shipping conditions
RRID
Product Specific Information
Immunogen sequence: PPITNLRMKA KAQQLTWDLN RNVTDIECVK DADYSMPAVN NSYCQFGAIS LCEVTNYTVR VANPPFSTWI LFPENSGKPW AGAENLTCWI HDVDFLSCSW AVGPGAPADV QYDLYLNVAN RRQQYECLHY KTDAQGTRIG CRFDDIS
Target Information
IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. IL-3Ra is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CD123; CD123 antigen; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; interleukin 3 receptor, alpha (low affinity); Interleukin-3 receptor subunit alpha
Gene Aliases: CD123; hIL-3Ra; IL3R; IL3RA; IL3RAY; IL3RX; IL3RY
UniProt ID: (Human) P26951
Entrez Gene ID: (Human) 3563
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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