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CD112 Polyclonal Antibody

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite CD112 Polyclonal Antibody

  • Antibody Testing Data (1)
CD112 Antibody in Flow Cytometry (Flow)
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CD112 Antibody in Flow Cytometry (Flow)
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CD112 Antibody (BS-2679R) in Flow

Human U937 cells probed with CD112 Polyclonal Antibody, Unconjugated (bs-2679R) (green) at 1:100 for 30 minutes followed by a PE conjugated secondary antibody compared to unstained cells (blue), secondary only (light blue), and isotype control (orange). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CD112 Antibody in Flow Cytometry (Flow)
CD112 Polyclonal Antibody

Product Details

BS-2679R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

Flow Cytometry (Flow)

1:100
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human nectin 2, amino acids 251-350.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD112; Herpes virus entry mediator B; Herpesvirus entry mediator B; herpesvirus entry protein B; hveB; mHveB; Murine herpes virus entry protein B; murine herpesvirus entry protein B; Nectin cell adhesion molecule 2; Nectin-2; Poliovirus receptor homolog; poliovirus receptor related 2; poliovirus receptor-like 2; poliovirus receptor-related 2 (herpesvirus entry mediator B); Poliovirus receptor-related protein 2; poliovirus sensitivity

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Gene Aliases: AI325026; AI987993; CD112; HVEB; MPH; nectin-2; NECTIN2; PRR2; Pvr; PVRL2; PVRR2; Pvs

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UniProt ID: (Human) Q92692, (Mouse) P32507

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Entrez Gene ID: (Human) 5819, (Rat) 308417, (Mouse) 19294

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Function(s)
virus receptor activity receptor binding protein binding coreceptor activity identical protein binding protein homodimerization activity protein heterodimerization activity cell adhesion molecule binding molecular_function
Process(es)
acrosome assembly positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target positive regulation of immunoglobulin mediated immune response cytoskeleton organization homophilic cell adhesion via plasma membrane adhesion molecules heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules signal transduction spermatid development spermatid nucleus differentiation cell recognition fertilization fusion of virus membrane with host plasma membrane sperm mitochondrion organization cell part morphogenesis positive regulation of mast cell activation adherens junction organization susceptibility to natural killer cell mediated cytotoxicity adhesion of symbiont to host cilium organization positive regulation of natural killer cell mediated cytotoxicity regulation of viral entry into host cell coreceptor-mediated virion attachment to host cell regulation of immune response establishment of mitochondrion localization susceptibility to T cell mediated cytotoxicity biological_process cell adhesion
It has to be done as per old AB suggested Products section.
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