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  • CD104 (Integrin beta 4) Antibodies

Invitrogen

CD104 (Integrin beta 4) Polyclonal Antibody

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Cite CD104 (Integrin beta 4) Polyclonal Antibody

  • Antibody Testing Data (1)
CD104 (Integrin beta 4) Antibody in Western Blot (WB)
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CD104 (Integrin beta 4) Antibody in Western Blot (WB)
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CD104 (Integrin beta 4) Antibody (PA5-79540) in WB

Western blot analysis of CD104 (Integrin beta 4) in A431 whole cell lysate using 40 µg per well. Sample was incubated with CD104 (Integrin beta 4) (Product # PA5-79540) at a dilution of 0.5 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CD104 (Integrin beta 4) Antibody in Western Blot (WB)
CD104 (Integrin beta 4) Polyclonal Antibody

Product Details

PA5-79540

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Integrin beta 4 (1810-1822aa TLSTHMDQQFFQT).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

500 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5mg BSA

Contains

0.05mg sodium azide, 0.05mg thimerosal

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2746655

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD antigen CD104; CD104; CD104 antigen; GP150; Integrin beta-4

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Gene Aliases: AA407042; C230078O20; CD104; GP150; ITGB4

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UniProt ID: (Human) P16144, (Mouse) A2A863, (Rat) Q64632

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Entrez Gene ID: (Human) 3691, (Mouse) 192897, (Rat) 25724

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Function(s)
G-protein coupled receptor binding receptor activity protein binding insulin-like growth factor I binding neuregulin binding cell adhesion molecule binding
Process(es)
autophagy cell adhesion cell-matrix adhesion integrin-mediated signaling pathway response to wounding extracellular matrix organization hemidesmosome assembly nail development skin development mesodermal cell differentiation digestive tract development cell motility renal system development amelogenesis cell communication filopodium assembly multicellular organism development
It has to be done as per old AB suggested Products section.
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