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Invitrogen
CAD Polyclonal Antibody
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Product Details
PA5-67042
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
Immunogen sequence: SHLPIVAHAEQ QTVAAVLMVA QLTQRSVHIC HVARKEEILL IKAAKARGLP VTCEVAPHHL FLSHDDLERL GPGKGEVRPE LGSRQDVEAL WENMAVIDCF ASDHAPHTLE EKCGSR
Highest antigen sequence identity to the following orthologs - mouse 89%, rat 89%.
Target Information
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CAD trifunctional protein; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; Multifunctional protein CAD
Gene Aliases: CAD; CDG1Z
UniProt ID: (Human) P27708
Entrez Gene ID: (Human) 790
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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