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Bioss
C8orf4 Polyclonal Antibody
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Product Details
BS-15289R
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Target Information
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: human thyroid cancer 1; TC-1; Thyroid cancer protein 1; thyroid cancer-1; Transcriptional and immune response regulator; uncharacterized protein C8orf4 homolog
Gene Aliases: 1110065B09Rik; AW121743; AW321058; C8orf4; TC-1; TC1; TCIM
UniProt ID: (Mouse) Q9D915, (Human) Q9NR00
Entrez Gene ID: (Mouse) 69068, (Human) 56892
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