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Invitrogen
C4BPA Polyclonal Antibody
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Product Details
PA5-81906
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Storage conditions
Shipping conditions
RRID
Product Specific Information
Immunogen sequence: CDKGYILVGQ AKLSCSYSHW SAPAPQCKAL CRKPELVNGR LSVDKDQYVE PENVTIQCDS GYGVVGPQSI TCSGNRTWYP EVPKCEWETP EGCEQVLTGK RLMQCLPNPE DVKMALEVYK LSLEIEQLEL QRDSARQST
Target Information
There are 3 variants of Complement component 4 binding protein (C4bp), which is composed of alpha and beta chains. The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. C4bp regulates the activation of the classical complement pathway. It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b. C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a. Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S. C4bp is expressed in the blood serum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: C4b-binding protein alpha chain; C4bp; Proline-rich protein; PRP; RP11-164O23.4
Gene Aliases: C4BP; C4BPA; PRP
UniProt ID: (Human) P04003
Entrez Gene ID: (Human) 722
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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