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  • Complement C3c Antibodies

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C3c Polyclonal Antibody, FITC

View all (41) Complement C3c antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite C3c Polyclonal Antibody, FITC

Product Details

GARA-C3C-FITC

Applications
Tested Dilution
Publications

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent
-

Immunocytochemistry (ICC/IF)

Assay-dependent
-

ELISA (ELISA)

Assay-dependent
-

Dot blot (DB)

Assay-dependent
-
Product Specifications

Species Reactivity

Rat

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Rat C3c

Conjugate

FITC FITC FITC

Excitation/Emission Max

498/517 nm View spectra spectra

Form

Lyophilized

Concentration

5-10 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstituted by adding 1 mL sterile distilled water, spun down to remove insoluble particles, divided into small aliquots, frozen and stored at or below -20°C.

The antiSerum does not cross-react with any other component of Rat plasma. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. Cross-reactivity of this antiSerum has not been tested in detail.

Prior to use, an aliquot is thawed slowly at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at +4°C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the immunoconjugate.

Target Information

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Complement C3

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Gene Aliases: C3

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UniProt ID: (Rat) P01026

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Entrez Gene ID: (Rat) 24232

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Function(s)
endopeptidase inhibitor activity protein binding lipid binding C5L2 anaphylatoxin chemotactic receptor binding cofactor binding
Process(es)
positive regulation of type IIa hypersensitivity positive regulation of protein phosphorylation positive regulation of activation of membrane attack complex tolerance induction fatty acid metabolic process chemotaxis inflammatory response complement activation complement activation, alternative pathway complement activation, classical pathway blood coagulation positive regulation of vascular endothelial growth factor production positive regulation of glucose transport regulation of triglyceride biosynthetic process positive regulation of lipid storage negative regulation of endopeptidase activity response to magnesium ion response to estradiol response to progesterone response to estrogen positive regulation of G-protein coupled receptor protein signaling pathway positive regulation of angiogenesis positive regulation of developmental growth positive regulation of phagocytosis response to glucocorticoid positive regulation of ERK1 and ERK2 cascade positive regulation of apoptotic cell clearance
It has to be done as per old AB suggested Products section.
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