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  • Primary Antibodies ›
  • C1 inhibitor Antibodies

Invitrogen

C1 inhibitor Polyclonal Antibody

View all (24) C1 inhibitor antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite C1 inhibitor Polyclonal Antibody

  • Antibody Testing Data (4)
C1 inhibitor Antibody in Immunocytochemistry (ICC/IF)
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C1 inhibitor Antibody in Immunocytochemistry (ICC/IF)
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C1 inhibitor Antibody (PA5-76028) in ICC/IF

Immunocytochemistry analysis of C1 inhibitor in NIH-3T3 cells. Samples were incubated with C1 inhibitor polyclonal antibody (Product # PA5-76028) using a dilution of 1:100. Blue: DAPI for nuclear staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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C1 inhibitor Antibody in Immunocytochemistry (ICC/IF)
C1 inhibitor Antibody in Immunocytochemistry (ICC/IF)
C1 inhibitor Antibody in Immunocytochemistry (ICC/IF)
C1 inhibitor Antibody in Western Blot (WB)
C1 inhibitor Polyclonal Antibody

Product Details

PA5-76028

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant full length Human C1 inhibitor.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2719756

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Target Information

C1-inhibitor (C1INH) functions as a regulator of the activation of the classical complement pathway and of the contact activation system of kinin generation and coagulation. Its primary biologically relevant target proteinases are C1r, C1s, coagulation factors XIa and XIIa, and plasma kallikrein. C1-inhibitor consists of one polypeptide chain and has a molecular mass of ~104 kDa. Serum concentration has been determined to 180 µg/mL.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: C1 esterase inhibitor; C1 Inh; C1 inhibitor; C1-inhibiting factor; C1Inh; complement component 1 inhibitor; esterase inhibitor; IC1; Plasma protease C1 inhibitor; serine (or cysteine) peptidase inhibitor, clade G, member 1; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary); serine (or cysteine) proteinase inhibitor, clade G, member 1; serine/cysteine proteinase inhibitor clade G member 1; Serpin G1; serpin peptidase inhibitor clade G member 1; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; serpin peptidase inhibitor, clade G, member 1

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Gene Aliases: C1IN; C1INH; C1NH; HAE1; HAE2; SERPING1

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UniProt ID: (Human) P05155, (Rat) Q6P734, (Mouse) P97290

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Entrez Gene ID: (Human) 710, (Rat) 295703, (Mouse) 12258

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Function(s)
serine-type endopeptidase inhibitor activity protein binding complement binding molecular_function peptidase inhibitor activity
Process(es)
negative regulation of complement activation, lectin pathway platelet degranulation complement activation, classical pathway aging blood coagulation, intrinsic pathway blood circulation negative regulation of endopeptidase activity fibrinolysis innate immune response blood coagulation biological_process immune system process hemostasis negative regulation of peptidase activity regulation of blood coagulation negative regulation of complement activation
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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