Bioss

C-erbB-2/HER2 Monoclonal Antibody (13H9), Cyanine3

View all (272) Her-2 (ErbB2) antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers
C-erbB-2/HER2 Monoclonal Antibody (13H9), Cyanine3

Product Details

BSM-33051M-CY3

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-5,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG

Class

Monoclonal

Type

Antibody

Clone

13H9

Immunogen

KLH conjugated synthetic peptide derived from human C-erbB-2/HER2
View immunogen

Conjugate

Cyanine3 Cyanine3 Cyanine3

Excitation/Emission Max

554/566 nm View spectra spectra

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.03% ProClin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); c-erb B2/neu protein; C-erbB-2; CD antigen CD340; CD340; epidermal growth factor receptor-related protein; erb-b2; erbb 2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; her 2; herstatin; human epidermal growth factor receptor 2; metas; Metastatic lymph node gene 19 protein; MLN 19; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; p185erbB2; p185neu; phospho ErbB2; Proto-oncogene c-ErbB-2; Proto-oncogene Neu; Receptor tyrosine-protein kinase erbB-2; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog

View more View less

Gene Aliases: c-erbB2; c-neu; CD340; Erbb-2; ERBB2; HER-2; HER-2/neu; HER2; Kiaa3023; mKIAA3023; MLN 19; MLN19; NEU; NGL; TKR1

View more View less

UniProt ID: (Human) P04626, (Mouse) P70424

View more View less

Entrez Gene ID: (Human) 2064, (Mouse) 13866, (Rat) 24337

View more View less

Function(s)
RNA polymerase I core binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity receptor signaling protein tyrosine kinase activity transmembrane signaling receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding protein C-terminus binding growth factor binding protein phosphatase binding identical protein binding ErbB-3 class receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity protein dimerization activity nucleotide binding glycoprotein binding protein kinase activity kinase activity transferase activity transferase activity, transferring phosphorus-containing groups ubiquitin protein ligase binding Hsp90 protein binding DNA binding
Process(es)
positive regulation of protein phosphorylation transcription, DNA-templated regulation of transcription, DNA-templated protein phosphorylation signal transduction cell surface receptor signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway nervous system development peripheral nervous system development heart development neuromuscular junction development motor neuron axon guidance positive regulation of cell proliferation glial cell differentiation phosphatidylinositol 3-kinase signaling positive regulation of phosphatidylinositol 3-kinase signaling phosphorylation peptidyl-tyrosine phosphorylation positive regulation of cell growth regulation of microtubule-based process negative regulation of immature T cell proliferation in thymus wound healing myelination negative regulation of apoptotic process positive regulation of MAP kinase activity positive regulation of MAPK cascade positive regulation of GTPase activity estrous cycle positive regulation of translation positive regulation of cell adhesion positive regulation of transcription from RNA polymerase I promoter positive regulation of transcription from RNA polymerase III promoter positive regulation of Ras protein signal transduction protein autophosphorylation sympathetic nervous system development response to axon injury oligodendrocyte differentiation positive regulation of epithelial cell proliferation regulation of ERK1 and ERK2 cascade liver development central nervous system development skeletal muscle tissue development signal transduction by protein phosphorylation response to progesterone regulation of cell proliferation response to drug tongue development regulation of cell differentiation mammary gland involution MAPK cascade enzyme linked receptor protein signaling pathway cell proliferation regulation of phosphatidylinositol 3-kinase signaling ERBB2 signaling pathway regulation of angiogenesis phosphatidylinositol phosphorylation phosphatidylinositol-mediated signaling cellular response to growth factor stimulus cellular response to epidermal growth factor stimulus positive regulation of protein targeting to membrane regulation of cell motility
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support