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  • Primary Antibodies ›
  • Blimp-1 Antibodies

Invitrogen

Blimp-1 Monoclonal Antibody (7C11H1)

View all (37) Blimp-1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Blimp-1 Monoclonal Antibody (7C11H1)

Blimp-1 Monoclonal Antibody (7C11H1)

Product Details

MA5-48389

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (IHC)

Assay-dependent
-

Immunocytochemistry (ICC/IF)

Assay-dependent
-

Flow Cytometry (Flow)

1:200-1:400
-

ELISA (ELISA)

1:10,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

7C11H1

Immunogen

Purified recombinant fragment of human PRDM1 (AA: 690-825) expressed in E. Coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3090822

Target Information

Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein with five zinc fingers in its carboxy terminus. It is a transcriptional repressor that is both required and sufficient to trigger terminal differentiation of B lymphocytes and monocyte/macrophages. Blimp-1 is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells. It has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: B-lymphocyte-induced maturation protein 1; Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP 1; BLIMP-1; MGC118922; MGC118923; MGC118924; MGC118925; OTTHUMP00000016918; OTTHUMP00000202173; Positive regulatory domain I-binding factor 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PRDI BF1; PRDI-BF1; PRDI-binding factor-1; RP1-134E15.1

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Gene Aliases: BLIMP1; PRDI-BF1; PRDM1

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UniProt ID: (Human) O75626

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Entrez Gene ID: (Human) 639

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Function(s)
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding protein binding methyltransferase activity histone deacetylase binding metal ion binding promoter-specific chromatin binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter morphogenesis of a branching structure maternal placenta development heart valve development ventricular septum development transcription, DNA-templated germ cell development post-embryonic development positive regulation of gene expression negative regulation of B cell proliferation negative regulation of lipopolysaccharide-mediated signaling pathway methylation regulation of natural killer cell differentiation regulation of extrathymic T cell differentiation aorta development eye photoreceptor cell development cell fate commitment positive regulation of B cell differentiation artery morphogenesis regulation of NK T cell differentiation intestinal epithelial cell development trophoblast giant cell differentiation coronary vasculature development sebum secreting cell proliferation
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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