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  • Primary Antibodies ›
  • POU3F2 Antibodies

Proteintech

BRN2 Polyclonal Antibody

3 References
View all (15) POU3F2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite BRN2 Polyclonal Antibody

  • Antibody Testing Data (6)
BRN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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BRN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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BRN2 Antibody (18998-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using (Product # 18998-1-AP) (BRN2-Specific antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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BRN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
BRN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
BRN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
BRN2 Antibody in Western Blot (WB)
BRN2 Antibody in Western Blot (WB)
BRN2 Antibody in Western Blot (WB)

Product Details

18998-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.36 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Target Information

This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 7-Oct; Brain-2; brain-2 class III POU-domain protein; Brain-specific homeobox/POU domain protein 2; Nervous system-specific octamer-binding transcription factor N-Oct-3; Oct-7; Octamer-binding protein 7; Octamer-binding transcription factor 7; OTF-7; POU domain, class 3, transcription factor 2; protein Brn-2

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Gene Aliases: 9430075J19Rik; A230098E07Rik; Brn-2; BRN2; N-Oct3; oct-7; OCT7; OTF-7; OTF7; POU3F2; POUF3

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UniProt ID: (Human) P20265, (Mouse) P31360

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Entrez Gene ID: (Human) 5454, (Mouse) 18992, (Rat) 29588

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Function(s)
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription coactivator activity transcription factor activity, sequence-specific DNA binding protein binding identical protein binding DNA binding sequence-specific DNA binding HMG box domain binding
Process(es)
transcription from RNA polymerase II promoter positive regulation of cell proliferation epidermis development negative regulation of gene expression astrocyte development cerebral cortex radially oriented cell migration forebrain ventricular zone progenitor cell division hypothalamus cell differentiation neurohypophysis development myelination in peripheral nervous system neuron differentiation positive regulation of multicellular organism growth positive regulation of transcription from RNA polymerase II promoter regulation of axonogenesis cellular response to organic substance transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter Schwann cell development regulation of cell differentiation
It has to be done as per old AB suggested Products section.
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