Invitrogen

BCL11B Polyclonal Antibody

Name: BCL11B Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-100794

View all (15) BCL11B antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (3)

BCL11B Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 3

BCL11B Antibody (PA5-100794) in ICC/IF

Immunocytochemistry analysis of BCL11B in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with BCL11B polyclonal antibody (Product # PA5-100794) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).

BCL11B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Immunogen image

Immunogen Image BCL11B Polyclonal Antibody

Product Details

PA5-100794

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

Immunocytochemistry (ICC/IF)

1:100-1:500

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human BCL11B(Accession Q9C0K0), corresponding to amino acid residues G284-E334.

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2850297

Product Specific Information

Antibody detects endogenous levels of total BCL11B.

Target Information

This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: B-cell CLL/lymphoma 11B; B-cell CLL/lymphoma 11B (zinc finger protein); B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein; B-cell leukemia/lymphoma 11B; B-cell lymphoma/leukaemia 11B; B-cell lymphoma/leukemia 11B; BCL-11B; BCL11B/TRDC fusion; COUP-TF-interacting protein 2; COUP-TF-interacting protein 2 long form; hRit1; Radiation-induced tumor suppressor gene 1 protein; zinc f; zinc finger protein hRit1 alpha

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Gene Aliases: ATL1; ATL1-alpha; ATL1-beta; ATL1-delta; ATL1-gamma; BCL11B; CTIP-2; CTIP2; hRIT1-alpha; RIT1; ZNF856B

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UniProt ID: (Human) Q9C0K0

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Entrez Gene ID: (Human) 64919, (Rat) 314423

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Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding protein binding sequence-specific DNA binding transcription regulatory region DNA binding metal ion binding

Process(es)

keratinocyte development epithelial cell morphogenesis transcription from RNA polymerase II promoter axonogenesis negative regulation of cell proliferation post-embryonic development regulation of gene expression regulation of keratinocyte proliferation regulation of lipid metabolic process striatal medium spiny neuron differentiation commitment of neuronal cell to specific neuron type in forebrain central nervous system neuron differentiation post-embryonic camera-type eye development T cell differentiation in thymus T cell receptor V(D)J recombination odontogenesis of dentin-containing tooth negative regulation of apoptotic process positive T cell selection skin development regulation of neuron differentiation positive regulation of transcription from RNA polymerase II promoter alpha-beta T cell differentiation thymus development olfactory bulb axon guidance signal transduction neurogenesis

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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BCL11B Polyclonal Antibody

BCL11B Antibody (PA5-100794) in ICC/IF

Product Details

PA5-100794

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

References (0)

Bioinformatics

Performance Guarantee

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