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Proteintech
Autotaxin Polyclonal Antibody
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Product Details
14243-1-AP
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: AHRIKRAEG WEEGPPTVLS DSPWTNISGS CKGRCFELQE AGPPDCRCDN LCKSYTSCCH DFDELCLKTA RGWECTKDRC GEVRNEENAC HCSEDCLARG DCCTNYQVVC KGESHWVDDD CEEIKAAECP AGFVRPPLII FSVDGFRASY MKKGSKVMPN IEKLRSCGTH SPYMRPVYPT KTFPNLYTLA TGLYPESHGI VGNSMYDPVF DATFHLRGRE KFNHRWWGGQ PLWITATKQG VKAGTFFWSV VIPHERRILT ILQWLTLPDH ERPSVYAFYS EQPDFSGHKY GPFGPEMTNP LREIDKIVGQ LMDGLKQLKL HRCVNVIFVG DHGMEDVTCD RTEFLSNYLT NVDDI (30-383 aa encoded by B C034961)
Target Information
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Autotaxin; autotaxin-t; AutotaxinATX; E-NPP 2; Ectonucleotide pyrophosphatase/phosphodiesterase family member 2; Extracellular lysophospholipase D; FLJ26803; LysoPLD; phosphodiesterase I/nucleotide pyrophosphatase 2; phosphodiesterase I/nucleotide pyrophosphatase 2 (autotaxin); plasma lysophospholipase D
Gene Aliases: ATX; ATX-X; AUTOTAXIN; ENPP2; LysoPLD; NPP2; Npps2; PD-IALPHA; PDNP2
UniProt ID: (Human) Q13822, (Mouse) Q9R1E6, (Rat) Q64610
Entrez Gene ID: (Human) 5168, (Mouse) 18606, (Rat) 84050
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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