Proteintech

Apolipoprotein A II Polyclonal Antibody

3 References
View all (21) ApoA2 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers
Apolipoprotein A II Polyclonal Antibody

Product Details

16845-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500
-

Immunocytochemistry (ICC/IF)

1:50
-

Immunoprecipitation (IP)

0.5-4.0 µg
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Apolipoprotein A II Fusion Protein Ag9863 (1-100 aa encoded by BC005282)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MKLLAATVL LLTICSLEGA LVRRQAKEPC VESLVSQYFQ TVTDYGKDLM EKVKSPELQA EAKSYFEKSK EQLTPLIKKA GTELVNFLSY FVELGTQPAT Q (1-100 aa encoded by BC005282)

Target Information

At least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL, and VLDL particles of human serum are often used to estimate an individual's relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins ( especially A-1 and B) have been suggested to be more accurate estimators of coronary heart disease that measurements of lipoprotein particles (especially HDL and LDL). The apolipoproteins are derived from human plasma by density gradient ultracentrifugation and HPLC.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: APO A2; Apo-AII; Apolipoprotein; Apolipoprotein A-II; Apolipoprotein A2; Apolipoprotein AII

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Gene Aliases: Apo-AII; ApoA-II; APOA2; apoAII

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UniProt ID: (Human) P02652

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Entrez Gene ID: (Human) 336

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Function(s)
lipid transporter activity protein binding phospholipid binding high-density lipoprotein particle binding lipid binding cholesterol binding cholesterol transporter activity phosphatidylcholine binding apolipoprotein receptor binding protein homodimerization activity protein heterodimerization activity lipase inhibitor activity phosphatidylcholine-sterol O-acyltransferase activator activity high-density lipoprotein particle receptor binding
Process(es)
retinoid metabolic process acute inflammatory response negative regulation of cytokine secretion involved in immune response triglyceride metabolic process phosphatidylcholine biosynthetic process cholesterol metabolic process phospholipid catabolic process response to glucose positive regulation of cholesterol esterification negative regulation of very-low-density lipoprotein particle remodeling viral process protein oxidation peptidyl-methionine modification regulation of intestinal cholesterol absorption organ regeneration regulation of protein stability negative regulation of cholesterol transport cholesterol efflux phospholipid efflux triglyceride-rich lipoprotein particle remodeling low-density lipoprotein particle remodeling high-density lipoprotein particle remodeling high-density lipoprotein particle assembly high-density lipoprotein particle clearance lipoprotein metabolic process lipoprotein biosynthetic process response to drug cholesterol homeostasis positive regulation of catalytic activity response to estrogen reverse cholesterol transport positive regulation of interleukin-8 biosynthetic process diacylglycerol catabolic process negative regulation of lipid catabolic process positive regulation of lipid catabolic process response to glucocorticoid negative regulation of lipase activity negative regulation of cholesterol import negative regulation of cholesterol transporter activity
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