Proteintech

Annexin A2 Monoclonal Antibody (1C1E12)

Name: Annexin A2 Monoclonal Antibody (1C1E12)
Brand: Proteintech
SKU: 66035-1-IG

28 References

View all (38) Annexin A2 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (16)

Annexin A2 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 16

Annexin A2 Antibody (66035-1-IG) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed T-47D cells using Annexin A2 antibody (Product # 66035-1-Ig), at dilution of 1:500 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L).

Annexin A2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Annexin A2 Antibody in Western Blot (WB)

Annexin A2 Antibody in Flow Cytometry (Flow)

Product Image Gallery

Immunogen image

Immunogen Image Annexin A2 Monoclonal Antibody (1C1E12)

Product Details

66035-1-IG

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 10 publications 10 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:250-1:1,000

Immunocytochemistry (ICC/IF)

1:20-1:200

View 7 publications 7 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

Assay-dependent

View 5 publications 5 publications

Miscellaneous PubMed (MISC)

View 1 publication 1 publication

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

1C1E12

Immunogen

Annexin A2 Fusion Protein Ag16654 (1-339 aa encoded by BC016774)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSTVHEILC KLSLEGDHST PPSAYGSVKA YTNFDAERDA LNIETAIKTK GVDEVTIVNI LTNRSNAQRQ DIAFAYQRRT KKELASALKS ALSGHLETVI LGLLKTPAQY DASELKASMK GLGTDEDSLI EIICSRTNQE LQEINRVYKE MYKTDLEKDI ISDTSGDFRK LMVALAKGRR AEDGSVIDYE LIDQDARDLY DAGVKRKGTD VPKWISIMTE RSVPHLQKVF DRYKSYSPYD MLESIRKEVK GDLENAFLNL VQCIQNKPLY FADRLYDSMK GKGTRDKVLI RIMVSRSEVD MLKIRSEFKR KYGKSLYYYI QQDTKGDYQK ALLYLCGGDD (1-339 aa encoded by BC016774)

Target Information

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 33-kDa calcimedin; 33-kDa lymphocyte Ca<2+>- binding protein; 33kDa lymphocyte Ca<2+>- binding protein; 36-kDa calelectrin; Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; calpactin I heavy polypeptide; Calpactin-1 heavy chain; chromobindin 8; Chromobindin-8; epididymis secretory protein Li 270; Lipocortin II; p36; PAP-IV; Placental anticoagulant protein IV; Protein I

View more View less

Gene Aliases: ANX2; ANX2L4; ANXA2; AW215814; CAL1H; HEL-S-270; LIP2; LPC2; LPC2D; P36; PAP-IV

View more View less

UniProt ID: (Human) P07355, (Mouse) P07356, (Rat) Q07936

View more View less

Entrez Gene ID: (Human) 302, (Mouse) 12306, (Rat) 56611

View more View less

Function(s)

protease binding calcium ion binding protein binding calcium-dependent phospholipid binding phosphatidylinositol-4,5-bisphosphate binding cytoskeletal protein binding Rab GTPase binding phospholipase A2 inhibitor activity receptor activator activity S100 protein binding poly(A) RNA binding calcium-dependent protein binding cadherin binding involved in cell-cell adhesion phospholipase inhibitor activity actin filament binding

Process(es)

angiogenesis membrane raft assembly positive regulation of protein phosphorylation negative regulation of receptor internalization membrane budding body fluid secretion collagen fibril organization positive regulation of vesicle fusion negative regulation of low-density lipoprotein particle receptor catabolic process osteoclast development fibrinolysis negative regulation of catalytic activity positive regulation of fibroblast proliferation positive regulation of binding protein heterotetramerization cellular response to acid chemical protein targeting to plasma membrane negative regulation of receptor binding positive regulation of receptor activity response to thyroid hormone cell-cell adhesion regulation of fibrinolysis

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

Annexin A2 Monoclonal Antibody (1C1E12)

Annexin A2 Antibody (66035-1-IG) in ICC/IF

Product Details

66035-1-IG

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!