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  • Primary Antibodies ›
  • SNAP alpha Antibodies

Fabgennix

Alpha SNAP Polyclonal Antibody, FITC

View all (15) SNAP alpha antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Alpha SNAP Polyclonal Antibody, FITC

Alpha SNAP Polyclonal Antibody, FITC

Product Details

SNAP-FITC

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (IHC)

1:50-1:250
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:50-1:250
-
Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide taken within amino acid region 195-245 on human alpha-soluble NSF attachment protein.
View immunogen

Conjugate

FITC FITC FITC

Excitation/Emission Max

498/517 nm View spectra spectra

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-to-endosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. a-SNAP (or b-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: alpha snap; alpha soluble NSF attachment protein; alpha-SNAP; Alpha-soluble NSF attachment protein; hydrocephaly with hop gait; N-ethylmaleimide sensitive fusion protein attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein, alpha; SNAP-alpha

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Gene Aliases: 1500039N14Rik; a-SNAP; alpha-SNAP; AW209189; hyh; NAPA; RA81; Snap; SNAPA; SNARE

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UniProt ID: (Human) P54920, (Rat) P54921, (Mouse) Q9DB05

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Entrez Gene ID: (Pig) 100515953, (Human) 8775, (Rat) 140673, (Mouse) 108124

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Function(s)
soluble NSF attachment protein activity protein binding syntaxin binding SNARE binding
Process(es)
intracellular protein transport brain development regulation of synaptic vesicle priming neuron differentiation synaptic transmission, glutamatergic SNARE complex disassembly apical protein localization membrane fusion transport protein transport vesicle-mediated transport ER to Golgi vesicle-mediated transport retrograde vesicle-mediated transport, Golgi to ER intra-Golgi vesicle-mediated transport COPII vesicle coating
It has to be done as per old AB suggested Products section.
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