Bioss

Adenosine deaminase Polyclonal Antibody

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Datasheet
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Datasheet
Protocols
Questions & Answers
Adenosine deaminase Polyclonal Antibody

Product Details

BS-6654R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Adenosine deaminase, amino acids 65-170.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Adenosine aminohydrolase; Adenosine deaminase; RP11-61L14.5

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Gene Aliases: ADA; ADA1

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UniProt ID: (Human) P00813, (Mouse) P03958, (Rat) Q920P6

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Entrez Gene ID: (Human) 100, (Mouse) 11486, (Rat) 24165

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Function(s)
purine nucleoside binding adenosine deaminase activity protein binding zinc ion binding hydrolase activity deaminase activity metal ion binding
Process(es)
response to hypoxia in utero embryonic development histamine secretion trophectodermal cell differentiation liver development placenta development germinal center B cell differentiation positive regulation of germinal center formation negative regulation of leukocyte migration negative regulation of mature B cell apoptotic process adenosine catabolic process deoxyadenosine catabolic process cell adhesion nucleotide metabolic process purine ribonucleoside monophosphate biosynthetic process positive regulation of heart rate lung development positive regulation of B cell proliferation purine nucleotide salvage positive regulation of T cell differentiation in thymus response to vitamin E regulation of cell-cell adhesion mediated by integrin T cell activation negative regulation of circadian sleep/wake cycle, non-REM sleep negative regulation of apoptotic process hypoxanthine salvage response to morphine regulation of T cell differentiation positive regulation of T cell differentiation positive regulation of smooth muscle contraction dATP catabolic process adenosine metabolic process hypoxanthine biosynthetic process inosine biosynthetic process xanthine biosynthetic process positive regulation of alpha-beta T cell differentiation lung alveolus development Peyer's patch development embryonic digestive tract development negative regulation of inflammatory response positive regulation of calcium-mediated signaling positive regulation of T cell receptor signaling pathway positive regulation of T cell activation negative regulation of adenosine receptor signaling pathway negative regulation of penile erection negative regulation of thymocyte apoptotic process negative regulation of mucus secretion aging response to drug response to hydrogen peroxide regulation of circadian sleep/wake cycle, sleep purine-containing compound salvage
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