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Invitrogen
Actin-like 7A Polyclonal Antibody
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Product Details
PA5-113542
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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RRID
Target Information
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: actin-like 7-alpha; actin-like 7A; Actin-like protein 7A; actin-like Tact2; Actin-like-7-alpha; t-actin 2; T-actin-2; testicular secretory protein Li 3; Testis-specific actin-2
Gene Aliases: ACTL7A; Tact2
UniProt ID: (Human) Q9Y615, (Mouse) Q9QY84
Entrez Gene ID: (Human) 10881, (Mouse) 11470
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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