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Invitrogen
Acinus Polyclonal Antibody
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FIGURE: 1 / 6
Acinus Antibody (PA5-19938) in ICC/IF
Product Details
PA5-19938
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Purification
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RRID
Product Specific Information
In Western blot applications, this antibody detects a band at ~220kDa. A suggested positive control is K562 cell lysate.
PA5-19938 can be used with blocking peptide PEP-0063.
Target Information
ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Acinus; Apoptotic chromatin condensation inducer in the nucleus; DKFZp667N107; functional spliceosome-associated protein 152
Gene Aliases: ACIN1; ACINUS; ACN; fSAP152; KIAA0670
UniProt ID: (Human) Q9UKV3
Entrez Gene ID: (Human) 22985
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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