Proteintech

ATG7 Monoclonal Antibody (2B5A10)

25 References
View all (29) ATG7 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

67341-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:5,000
View 21 publications 21 publications

Immunohistochemistry (IHC)

-
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000
-

Immunocytochemistry (ICC/IF)

1:100
View 3 publications 3 publications
Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

2B5A10

Immunogen

ATG7 Fusion Protein Ag29172

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1000 µg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Aliquoting is unnecessary for -20°C storage.

Target Information

This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: APG7-like; ATG12-activating enzyme E1 ATG7; ATG7 autophagy related 7 homolog; autophagy related 7 homolog; autophagy-related 7; Autophagy-related protein 7; DKFZp434N0735; hAGP7; Ubiquitin-activating enzyme E1-like protein; Ubiquitin-like modifier-activating enzyme ATG7

View more View less

Gene Aliases: 1810013K23Rik; Agp7; APG7-LIKE; APG7L; ATG7; Atg7l; Gm21553; GSA7

View more View less

UniProt ID: (Human) O95352, (Rat) Q641Y5, (Mouse) Q9D906

View more View less

Entrez Gene ID: (Human) 10533, (Pig) 100462749, (Rat) 312647, (Mouse) 74244

View more View less

Function(s)
ubiquitin activating enzyme activity protein binding transcription factor binding Atg12 activating enzyme activity Atg8 activating enzyme activity protein homodimerization activity molecular_function small protein activating enzyme activity
Process(es)
cellular protein modification process protein lipidation C-terminal protein lipidation cellular response to nitrogen starvation cellular response to starvation positive regulation of autophagy protein transport macroautophagy positive regulation of macroautophagy protein ubiquitination positive regulation of protein modification process piecemeal microautophagy of nucleus suppression by virus of host autophagy positive regulation of apoptotic process late nucleophagy positive regulation of protein catabolic process defense response to virus membrane fusion cellular response to hyperoxia regulation of mitophagy mitophagy liver development cellular amino acid metabolic process autophagy organelle organization mitochondrion organization adult walking behavior post-embryonic development cerebellar Purkinje cell layer development pyramidal neuron development central nervous system neuron axonogenesis cerebral cortex development protein catabolic process neuron projection development regulation of protein ubiquitination protein modification by small protein conjugation negative stranded viral RNA replication response to starvation negative regulation of apoptotic process neurological system process cardiac muscle cell development membrane organization positive regulation of mucus secretion negative regulation of histone H4-K16 acetylation autophagosome assembly transport regulation of cell development negative regulation of cell death regulation of hemopoiesis
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support