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  • ARX Antibodies

Invitrogen

ARX Polyclonal Antibody

View all (20) ARX antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ARX Polyclonal Antibody

  • Antibody Testing Data (1)
ARX Antibody in Western Blot (WB)
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ARX Antibody in Western Blot (WB)
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ARX Antibody (PA5-142412) in WB

Western Blot analysis of ARX in Human Frontal Cortex lysate (35 µg protein in RIPA buffer) using ARX Polyclonal Antibody (Product # PA5-142412) at 0.5 µg/mL incubated for 1 hour. Detected by chemiluminescence. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ARX Antibody in Western Blot (WB)
ARX Polyclonal Antibody

Product Details

PA5-142412

Applications
Tested Dilution
Publications

Western Blot (WB)

0.5-1 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide with sequence C-QVSISRSKSYREN (aa 166-178).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2933060

Product Specific Information

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:1,000.

Target Information

Arx contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This protein is thought to be involved in CNS development. Mutations in the Arx gene cause X-linked mental retardation and epilepsy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Aristaless-related homeobox; aristaless-related homeobox, X-linked; cancer/testis antigen 121; Homeobox protein ARX

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Gene Aliases: ARX; CT121; EIEE1; ISSX; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRX76; MRX87; MRXS1; PRTS

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UniProt ID: (Human) Q96QS3

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Entrez Gene ID: (Human) 170302

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Function(s)
RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding chromatin binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated axon guidance positive regulation of gene expression globus pallidus development cerebral cortex tangential migration embryonic olfactory bulb interneuron precursor migration cell proliferation in forebrain cerebral cortex GABAergic interneuron migration regulation of cell proliferation lipid digestion positive regulation of organ growth epithelial cell fate commitment
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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