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Invitrogen
ARTS Polyclonal Antibody
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Product Details
PA5-82767
Species Reactivity
Published species
Host/Isotype
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Type
Immunogen
Conjugate
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Product Specific Information
Immunogen sequence: YDDDLEFRPP SRPQSSDNQQ YFCAPAPLSP SARPRSPWGK LDPYDSSEDD KEYVGFATLP NQVHRKS
Target Information
Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 4-Sep; apoptosis-related protein in the TGF-beta signaling pathway; Bradeion beta; Brain protein H5; CE5B3 beta; Cell division control-related protein 2; cerebral protein 7; hCDCREL-2; Peanut-like protein 2; Septin-4; septin-M
Gene Aliases: ARTS; BRADEION; C17orf47; CE5B3; H5; hCDCREL-2; hucep-7; MART; PNUTL2; SEP4; SEPT4; SEPTIN4
UniProt ID: (Human) O43236
Entrez Gene ID: (Human) 5414
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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