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ARHGDIB Monoclonal Antibody (2C12-B6)

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite ARHGDIB Monoclonal Antibody (2C12-B6)

  • Antibody Testing Data (1)
ARHGDIB Antibody in ELISA (ELISA)
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ARHGDIB Antibody in ELISA (ELISA)
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ARHGDIB Antibody (H00000397-M01) in ELISA

Detection limit for recombinant GST tagged ARHGDIB is approximately 3 ng/mL as a capture antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ARHGDIB Antibody in ELISA (ELISA)
ARHGDIB Monoclonal Antibody (2C12-B6)

Product Details

H00000397-M01

Applications
Tested Dilution
Publications

ELISA (ELISA)

3 ng/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

2C12-B6

Immunogen

ARHGDIB (AAH09200, 1 a.a. approximately 201 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MTEKAPEPHV EEDDDDELDS KLNYKPPPQK SLKELQEMDK DDESLIKYKK TLLGDGPVVT DPKAPNVVVT RLTLVCESAP GPITMDLTGD LEALKKETIV LKEGSEYRVK IHFKVNRDIV SGLKYVQHTY RTGVKVDKAT FMVGSYGPRP EEYEFLTPVE EAPKGMLARG TYHNKSFFTD DDKQDHLSWE WNLSIKKEWT E

Target Information

Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: d4 gdi; GDI LYGDI; Ly-GDI; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; Rho GDP-dissociation inhibitor 2; Rho-GDI beta

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Gene Aliases: ARHGDIB; D4; GDIA2; GDID4; Ly-GDI; LYGDI; RAP1GN1; RhoGDI2

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UniProt ID: (Human) P52566

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Entrez Gene ID: (Human) 397

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Function(s)
GTPase activity Rho GDP-dissociation inhibitor activity GTPase activator activity protein binding Rac GTPase binding
Process(es)
movement of cell or subcellular component negative regulation of cell adhesion multicellular organism development regulation of Rho protein signal transduction positive regulation of GTPase activity regulation of small GTPase mediated signal transduction cellular response to redox state negative regulation of trophoblast cell migration regulation of actin cytoskeleton reorganization
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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