OriGene

AQP1 Monoclonal Antibody (OTI10C11), TrueMAB™

View all (33) Aquaporin 1 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers
AQP1 Monoclonal Antibody (OTI10C11), TrueMAB™

Product Details

CF502356

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Flow Cytometry (Flow)

1:100
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI10C11

Immunogen

Full length human recombinant protein of human AQP1 produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: AQP 1; AQP CHIP; AQP-1; aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1, Colton blood group antigen; Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; Channel-like integral membrane protein of 28 kDa; channel-like integral membrane protein, 28-kDa; CHIP 28; Colton blood group; MGC26324; Urine water channel; water channel protein for red blood cells and kidney proximal tubule

View more View less

Gene Aliases: AQP-CHIP; AQP1; CHIP28; CO

View more View less

UniProt ID: (Human) P29972

View more View less

Entrez Gene ID: (Human) 358

View more View less

Function(s)
intracellular cGMP activated cation channel activity potassium channel activity water transmembrane transporter activity protein binding ammonium transmembrane transporter activity potassium ion transmembrane transporter activity glycerol transmembrane transporter activity water channel activity glycerol channel activity transmembrane transporter activity nitric oxide transmembrane transporter activity carbon dioxide transmembrane transporter activity
Process(es)
renal water homeostasis renal water transport cGMP biosynthetic process potassium ion transport water transport cell volume homeostasis cellular water homeostasis carbon dioxide transport ammonium transport bicarbonate transport glycerol transport cellular homeostasis lateral ventricle development pancreatic juice secretion nitric oxide transport establishment or maintenance of actin cytoskeleton polarity cerebrospinal fluid secretion cellular response to stress cellular response to UV transepithelial water transport carbon dioxide transmembrane transport odontogenesis response to drug negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of angiogenesis positive regulation of saliva secretion positive regulation of fibroblast proliferation multicellular organismal water homeostasis cellular response to hydrogen peroxide cellular response to inorganic substance cellular response to mechanical stimulus cellular response to copper ion cellular response to mercury ion cellular response to retinoic acid cellular response to cAMP cellular response to hypoxia cellular response to salt stress cellular hyperosmotic response cellular response to dexamethasone stimulus cellular response to nitric oxide potassium ion transmembrane transport ammonium transmembrane transport maintenance of symbiont-containing vacuole by host
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support