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  • AKR1B1 Antibodies

Invitrogen

AKR1B1 Polyclonal Antibody

View all (48) AKR1B1 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite AKR1B1 Polyclonal Antibody

  • Antibody Testing Data (6)
AKR1B1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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AKR1B1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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AKR1B1 Antibody (PA5-78750) in IHC (P)

Immunohistochemistry analysis of AKR1B1 on paraffin-embedded rat adrenal gland tissue. Sample was incubated with AKR1B1 polyclonal antibody (Product# PA5-78750) with a dilution of 1 µg/mL, and developed by Streptavidin-Biotin-Complex (SABC) with DAB chromogen method. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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AKR1B1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
AKR1B1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
AKR1B1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
AKR1B1 Antibody in Western Blot (WB)
AKR1B1 Antibody in Flow Cytometry (Flow)
AKR1B1 Antibody in Flow Cytometry (Flow)
AKR1B1 Polyclonal Antibody

Product Details

PA5-78750

Applications
Tested Dilution
Publications

Western Blot (WB)

0.1-0.5 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

0.5-1 µg/mL
-

Flow Cytometry (Flow)

1-3 µg/1x10^6 cells
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

E. coli-derived human AKR1B1 recombinant protein (Position: L228-F316).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

500 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5mg BSA

Contains

0.05mg sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2745866

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Positive Control - WB: human SiHa whole cell, rat testis tissue, mouse NIH/3T3 whole cell. IHC: rat intestine tissue, rat adrenal gland tissue, human placenta tissue. Flow: U20S cell.

Target Information

Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Aldehyde reductase; aldehyde reductase 1; Aldehyde reductase 1 (low Km aldose reductase) (5.8 kb PstI fragment, probably the functional gene); aldo-keto reductase family 1; Aldo-keto reductase family 1 member B1; Aldo-keto reductase family 1 member B3; aldo-keto reductase family 1, member B1 (aldose reductase); aldo-keto reductase family 1, member B4 (aldose reductase); Aldose reductase; AR; Lii5-2 CTCL tumor antigen; low Km aldose reductase; member B1 (aldose reductase)

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Gene Aliases: ADR; Ahr-1; Ahr1; AKR1B1; Akr1b3; Akr1b4; Aldor1; ALDR1; ALDRED; Alr; ALR-P-I; ALR2; AR; RATALDRED

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UniProt ID: (Human) P15121, (Rat) P07943, (Mouse) P45376

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Entrez Gene ID: (Human) 231, (Rat) 24192, (Mouse) 11677

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Function(s)
alditol:NADP+ 1-oxidoreductase activity aldo-keto reductase (NADP) activity electron carrier activity glyceraldehyde oxidoreductase activity oxidoreductase activity
Process(es)
tissue homeostasis monosaccharide metabolic process sorbitol biosynthetic process response to water deprivation response to organic substance naphthalene metabolic process stress-activated protein kinase signaling cascade norepinephrine metabolic process daunorubicin metabolic process doxorubicin metabolic process positive regulation of JAK-STAT cascade positive regulation of smooth muscle cell proliferation oxidation-reduction process cellular response to hydrogen peroxide inner medullary collecting duct development cellular response to methylglyoxal carbohydrate metabolic process C21-steroid hormone biosynthetic process response to stress fructose biosynthetic process maternal process involved in female pregnancy response to thyroid hormone cellular response to peptide
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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