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  • Primary Antibodies ›
  • AIP2 Antibodies

Invitrogen

AIP2 Polyclonal Antibody

View all (13) AIP2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite AIP2 Polyclonal Antibody

  • Antibody Testing Data (4)
AIP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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AIP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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AIP2 Antibody (PA5-42294) in IHC (P)

Immunohistochemistry (paraffin-embedded) analysis of human alveolar tissue using an anti-AIP2 / WWP2 polyclonal antibody (Product # PA5-42294). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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AIP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
AIP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
AIP2 Antibody in Western Blot (WB)
AIP2 Antibody in Western Blot (WB)

Product Details

PA5-42294

Applications
Tested Dilution
Publications

Western Blot (WB)

0.2-1 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

4-8 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the middle region of human WWP2

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2610526

Product Specific Information

Peptide sequence: EMKYTSEGVR YFVDHNTRTT TFKDPRPGFE SGTKQGSPGA YDRSFRWKYH

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%; Sheep: 100%; Zebrafish: 80%

Target Information

This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. The encoded protein contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AIP2; atrophin-1 interacting protein 2; Atrophin-1-interacting protein 2; HECT-type E3 ubiquitin transferase WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2; WW domain-containing protein 2

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Gene Aliases: AIP2; WWP2; WWp2-like

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UniProt ID: (Human) O00308

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Entrez Gene ID: (Human) 11060

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Function(s)
RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II transcription factor binding ubiquitin-protein transferase activity protein binding transcription factor binding ligase activity ubiquitin protein ligase activity
Process(es)
negative regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter cellular protein modification process negative regulation of gene expression protein ubiquitination negative regulation of transporter activity regulation of ion transmembrane transport regulation of membrane potential protein ubiquitination involved in ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process negative regulation of sequence-specific DNA binding transcription factor activity negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter viral entry into host cell negative regulation of protein transport protein autoubiquitination protein K63-linked ubiquitination regulation of potassium ion transmembrane transporter activity
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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