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AbboMax

AID Monoclonal Antibody (ZY201)

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite AID Monoclonal Antibody (ZY201)

  • Antibody Testing Data (1)
AID Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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AID Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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AID Antibody (604-040) in IHC (P)

Immunohistochemistry: Human colon carcinoma (FFPE) stained with Mouse anti-AID antibody (Cat# 604-040) at 1:200 for 10 min @ RT. Staining of formalin-fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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AID Antibody in Immunohistochemistry (Paraffin) (IHC (P))
AID Monoclonal Antibody (ZY201)

Product Details

604-040

Applications
Tested Dilution
Publications

Western Blot (WB)

0.1-1 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

2-10 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

ZY201

Immunogen

A recombinant protein of full length human AID
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS with proprietary stabilizer

Contains

0.01% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

Product Specific Information

Positive control: Chronic lymphocytic leukemia

Cellular location: Nucleus.

Target Information

This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Activation-induced cytidine deaminase; AID; Cytidine aminohydrolase; epididymis secretory protein Li 284; integrated into Burkitt's lymphoma cell line Ramos; Single-stranded DNA cytosine deaminase

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Gene Aliases: AICDA; AID; ARP2; CDA2; HEL-S-284; HIGM2

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UniProt ID: (Human) Q9GZX7

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Entrez Gene ID: (Human) 57379

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Function(s)
cytidine deaminase activity protein binding zinc ion binding ubiquitin protein ligase binding
Process(es)
mRNA processing cytidine deamination somatic diversification of immunoglobulins somatic hypermutation of immunoglobulin genes B cell differentiation isotype switching cellular response to lipopolysaccharide DNA demethylation negative regulation of methylation-dependent chromatin silencing
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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