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  • ADNP Antibodies

Invitrogen

ADNP Polyclonal Antibody

View all (13) ADNP antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ADNP Polyclonal Antibody

  • Antibody Testing Data (3)
ADNP Antibody in Immunocytochemistry (ICC/IF)
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ADNP Antibody in Immunocytochemistry (ICC/IF)
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ADNP Antibody (PA5-112243) in ICC/IF

Immunocytochemistry-Immunofluorescence analysis of ADNP in U2OS cells. Cells were fixed with 4% PFA, permeabilized with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with ADNP Polyclonal Antibody (Product # PA5-112243) (1:300) at 4°C overnight. Then cells were stained with the Alexa Fluor 594-conjugated Goat Anti-rabbit IgG secondary antibody (red). Positive staining was localized to Nucleus. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ADNP Antibody in Immunocytochemistry (ICC/IF)
ADNP Antibody in Western Blot (WB)
ADNP Antibody in Immunoprecipitation (IP)

Product Details

PA5-112243

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunocytochemistry (ICC/IF)

1:200-1:1,000
-

Immunoprecipitation (IP)

5-10 µL/mg of lysate
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

E. coli-derived Human activity-dependent neuroprotector homeobox/ADNP fragment

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS, pH 7

Contains

0.03% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2866979

Target Information

Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Activity-dependent neuroprotective protein; activity-dependent neuroprotector; Activity-dependent neuroprotector homeobox protein; ADNP homeobox 1

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Gene Aliases: ADNP; ADNP1; HVDAS; KIAA0784; MRD28

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UniProt ID: (Human) Q9H2P0

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Entrez Gene ID: (Human) 23394

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Function(s)
DNA binding chromatin binding copper ion binding protein binding peptide binding beta-tubulin binding
Process(es)
transcription, DNA-templated regulation of transcription, DNA-templated short-term memory response to carbohydrate response to inorganic substance negative regulation of gene expression regulation of protein ADP-ribosylation positive regulation of cGMP biosynthetic process cellular response to extracellular stimulus negative regulation of protein binding activation of protein kinase activity nitric oxide homeostasis negative regulation of neuron apoptotic process estrous cycle positive regulation of axon extension positive regulation of peptidyl-tyrosine phosphorylation negative regulation of synaptic transmission positive regulation of synapse assembly
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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