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  • ADAM2 Antibodies

Invitrogen

ADAM2 Polyclonal Antibody

Advanced Verification
View all (11) ADAM2 antibodies

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Questions & Answers

Cite ADAM2 Polyclonal Antibody

  • Antibody Testing Data (5)
  • Advanced Verification (1)
ADAM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ADAM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ADAM2 Antibody (PA5-55126) in IHC (P)

Immunohistochemical analysis of ADAM2 in human testis using ADAM2 Polyclonal Antibody (Product # PA5-55126) shows strong membranous and cytoplasmic positivity in cells in seminiferous ducts. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ADAM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ADAM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ADAM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ADAM2 Antibody in Immunohistochemistry (IHC)
ADAM2 Antibody in Immunohistochemistry (IHC)
ADAM2 Antibody
ADAM2 Polyclonal Antibody

Product Details

PA5-55126

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ADAM2. Recombinant protein control fragment (Product #RP-93765).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2637654

Product Specific Information

Immunogen sequence: CENCLFMSKE RMCRPSFEEC DLPEYCNGSS ASCPENHYVQ TGHPCGLNQW ICIDGVCMSG DK

Highest antigen sequence identity to the following orthologs: Mouse - 48%, Rat - 48%.

Target Information

ADAM2 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM2 is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: a disintegrin and metalloproteinase; ADAM; ADAM 2; ADAMs; Cancer/testis antigen 15; CT15; Disintegrin and metalloproteinase domain-containing protein 2; Fertilin subunit beta; metalloendopeptidases; PH-30; PH30; PH30-beta

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Gene Aliases: ADAM2; CRYN1; CRYN2; CT15; FTNB; PH-30b; PH30; PH30-beta

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UniProt ID: (Human) Q99965

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Entrez Gene ID: (Human) 2515

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Function(s)
metalloendopeptidase activity integrin binding metallopeptidase activity zinc ion binding
Process(es)
proteolysis cell adhesion binding of sperm to zona pellucida fusion of sperm to egg plasma membrane visual learning adult behavior
It has to be done as per old AB suggested Products section.
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