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  • Primary Antibodies ›
  • ADAM12 Antibodies

Invitrogen

ADAM12 Polyclonal Antibody

View all (19) ADAM12 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite ADAM12 Polyclonal Antibody

  • Antibody Testing Data (4)
ADAM12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ADAM12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ADAM12 Antibody (PA5-99969) in IHC (P)

Immunohistochemistry analysis of ADAM12 in human normal tissues adjacent to pancreatic cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with ADAM12 polyclonal antibody (Product # PA5-99969) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ADAM12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ADAM12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ADAM12 Antibody in Western Blot (WB)
ADAM12 Antibody in Western Blot (WB)
ADAM12 Polyclonal Antibody

Product Details

PA5-99969

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human ADAM12(Accession O43184), corresponding to amino acid residues M1-L33.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2818902

Product Specific Information

Antibody detects endogenous levels of total ADAM12.

Target Information

ADAM12 is a member of the ADAM (a disintegrin and metalloprotease-like domain) family. Two forms of ADAM12 have been described: ADAM12S and ADAM12L (short and long forms). The short form is a soluble form lacking the transmembrane and cytoplasmic domains. The short form of ADAM12 was reported to provoke myogenesis, and the lack of cytoplasmic domain suggests different regulation pathways (although both forms can be expressed in the same tissue).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: a disintegrin and metalloprotease domain 12; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 12 (meltrin alpha); ADAM; ADAM 12; ADAMs; Disintegrin and metalloproteinase domain-containing protein 12; meltrin alpha; Meltrin-alpha; metalloendopeptidases; metalloprotease-disintegrin 12 transmembrane; PRO545; RP11-295J3.5; UNQ346

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Gene Aliases: ADAM12; ADAM12-OT1; CAR10; MCMP; MCMPMltna; mKIAA4001; MLTN; MLTNA; UNQ346/PRO545

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UniProt ID: (Human) O43184, (Mouse) Q61824

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Entrez Gene ID: (Human) 8038, (Mouse) 11489

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Function(s)
metalloendopeptidase activity metallopeptidase activity zinc ion binding SH3 domain binding protein binding peptidase activity hydrolase activity metal ion binding
Process(es)
proteolysis cell adhesion myoblast fusion
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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