Disclaimer

Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

  • Primary Antibodies ›
  • alpha-Cardiac Actin Antibodies

Proteintech

ACTC1 Monoclonal Antibody (1F2B9)

9 References
View all (14) alpha-Cardiac Actin antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ACTC1 Monoclonal Antibody (1F2B9)

  • Antibody Testing Data (10)
ACTC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.
ACTC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.

FIGURE: 1 / 10

{{ $ctrl.currentElement.advancedVerification.fullName }}
{{ $ctrl.currentElement.advancedVerification.text }}

ACTC1 Antibody (66125-1-IG) in IHC (P)

Immunohistochemistry of paraffin-embedded human heart and human skeletal muscle using 66125-1-IG (ACTC1 specific antibody) at dilution 1:500. (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
Published figure supplied by benchsci-logo
PMID: {{$ctrl.currentElement.benchSciPubmedId}}
View Product

{{$ctrl.videoDesc}}

{{$ctrl.videoLongDesc}}

ACTC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ACTC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ACTC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ACTC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ACTC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ACTC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ACTC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ACTC1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
ACTC1 Antibody in Western Blot (WB)
ACTC1 Antibody in Western Blot (WB)

Product Details

66125-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2500-1:10,000
View 4 publications 4 publications

Immunohistochemistry (IHC)

-
View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:400
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:500
View 3 publications 3 publications
Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1F2B9

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated
  • CoraLite 594
  • CoraLite Plus 488
  • Request custom conjugation

Form

Liquid

Concentration

0.75 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody is specific to the ACTC1. It does not cross-react with other actin isoforms.

Target Information

ACTC1 are part of actins, which are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: actin alpha cardiac; actin alpha cardiac 1; Actin, alpha cardiac muscle 1; actin, alpha, cardiac 1; alpha-actin cardiac; Alpha-cardiac actin; alphac-actin; cardiac muscle alpha actin 1

View more View less

Gene Aliases: ACTC; Actc-1; ACTC1; ASD5; CMD1R; CMH11; LVNC4

View more View less

UniProt ID: (Human) P68032, (Mouse) P68033, (Rat) P68035

View more View less

Entrez Gene ID: (Human) 70, (Pig) 100152267, (Mouse) 11464, (Rat) 29275

View more View less

Function(s)
ATP binding ATPase activity myosin binding nucleotide binding protein binding
Process(es)
apoptotic process positive regulation of gene expression actin filament-based movement muscle filament sliding skeletal muscle thin filament assembly actomyosin structure organization actin-myosin filament sliding response to drug negative regulation of apoptotic process response to ethanol cardiac myofibril assembly cardiac muscle tissue morphogenesis heart contraction cardiac muscle contraction mesenchyme migration metabolic process actin-mediated cell contraction
It has to be done as per old AB suggested Products section.
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support

Your items have has been added!


Host server : magellan-search-56d64595f5-kjbpz:80/100.66.131.58:80.
git-commit: 7dd85a2aaed5e3122cf027567276b2918d4b9fce
git-url: https://github.com/thermofisher/magellan-search
git-branch: release/2.36.0-Offline