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  • ACSL3 Antibodies

Invitrogen

ACSL3 Monoclonal Antibody (A8F7)

View all (13) ACSL3 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ACSL3 Monoclonal Antibody (A8F7)

  • Antibody Testing Data (4)
ACSL3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ACSL3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ACSL3 Antibody (MA5-44923) in IHC (P)

Immunohistochemistry analysis of ACSL3 in paraffin-embedded human liver tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with ACSL3 Monoclonal antibody (Product # MA5-44923) using a dilution of 1:240 for 1 hour at room tempe... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ACSL3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ACSL3 Antibody in Western Blot (WB)
ACSL3 Antibody in Western Blot (WB)
ACSL3 Antibody in Western Blot (WB)
ACSL3 Monoclonal Antibody (A8F7)

Product Details

MA5-44923

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:5,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:240
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

A8F7

Immunogen

Recombinant protein within human ACSL3 aa 180-380.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 0.1% BSA, 40% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2931379

Target Information

An initial reaction in fatty acid metabolism in eukaryotic cells is activation of fatty acids catalyzed by acyl-CoA synthetase. FACL3 (fatty acid CoA ligase, long-chain 3) is identified as member of the acyl-CoA synthetase (ACS) family by PCR of rat brain cDNAs using primers based on the conserved region of the ACS protein. The 720-amino acid rat protein preferentially utilizes myristate, laurate, arachidonate, and eicosapentaenoate, and is expressed primarily in brain. The predicted 720-amino acid FACL3 human protein is 92% identical to that of rat.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Arachidonate--CoA ligase; Fatty acid CoA ligase Acsl3; fatty-acid-Coenzyme A ligase, long-chain 3; LACS 3; lignoceroyl-CoA synthase; Long-chain acyl-CoA synthetase 3; Long-chain-fatty-acid--CoA ligase 3; Medium-chain acyl-CoA ligase Acsl3

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Gene Aliases: ACS3; ACSL3; FACL3; LACS3; PRO2194

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UniProt ID: (Human) O95573

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Entrez Gene ID: (Human) 2181

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Function(s)
long-chain fatty acid-CoA ligase activity ATP binding protein kinase binding protein domain specific binding decanoate--CoA ligase activity
Process(es)
long-chain fatty acid metabolic process fatty acid biosynthetic process brain development response to nutrient response to organic cyclic compound very-low-density lipoprotein particle assembly long-chain fatty-acyl-CoA biosynthetic process positive regulation of Golgi to plasma membrane protein transport long-chain fatty acid import positive regulation of secretion positive regulation of phosphatidylcholine biosynthetic process
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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