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  • ACMSD Antibodies

Invitrogen

ACMSD Polyclonal Antibody

View all (7) ACMSD antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ACMSD Polyclonal Antibody

  • Antibody Testing Data (4)
ACMSD Antibody in Immunocytochemistry (ICC/IF)
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ACMSD Antibody in Immunocytochemistry (ICC/IF)
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ACMSD Antibody (PA5-113272) in ICC/IF

Immunocytochemichal analysis of ACMSD in HepG2 cells using a Polyclonal antibody (Product # PA5-113272) at a dilution of 1:100. An Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L) secondary antibdoy was used. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ACMSD Antibody in Immunocytochemistry (ICC/IF)
ACMSD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ACMSD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ACMSD Antibody in Western Blot (WB)
ACMSD Polyclonal Antibody

Product Details

PA5-113272

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:5,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase protein (33-129AA)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

4 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% ProClin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2868006

Target Information

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase

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Gene Aliases: ACMSD

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UniProt ID: (Human) Q8TDX5, (Rat) Q8R5M5

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Entrez Gene ID: (Human) 130013, (Rat) 171385

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Function(s)
aminocarboxymuconate-semialdehyde decarboxylase activity protein binding zinc ion binding hydrolase activity carboxy-lyase activity metal ion binding
Process(es)
tryptophan metabolic process nicotinamide metabolic process quinolinate metabolic process tryptophan catabolic process protein oligomerization regulation of quinolinate biosynthetic process picolinic acid biosynthetic process regulation of 'de novo' NAD biosynthetic process from tryptophan
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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