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Invitrogen
ACE Polyclonal Antibody
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FIGURE: 1 / 3
ACE Antibody (PA5-47964) in IHC (P)
Product Details
PA5-47964
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Concentration
Purification
Storage buffer
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RRID
Product Specific Information
In direct ELISAs, less than 10% cross-reactivity with recombinant mouse ACE is observed and less than 5% cross-reactivity with recombinant human ACE-2 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes-the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: ACE; angiotensin converting enzyme, somatic isoform; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript; Angiotensin-converting enzyme; carboxycathepsin; CD143; CD143 antigen; dipeptidyl carboxypeptidase 1; Dipeptidyl carboxypeptidase I; Kininase II; MGC26566; peptidase P; testicular ECA
Gene Aliases: ACE; ACE1; CD143; DCP; DCP1; ICH; MVCD3
UniProt ID: (Human) P12821
Entrez Gene ID: (Human) 1636
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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