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OriGene

ACD Monoclonal Antibody (OTI1C8), TrueMAB™

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Datasheet
Protocols
Questions & Answers

Cite ACD Monoclonal Antibody (OTI1C8), TrueMAB™

  • Antibody Testing Data (2)
ACD Antibody in Immunocytochemistry (ICC/IF)
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ACD Antibody in Immunocytochemistry (ICC/IF)
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ACD Antibody (TA504201) in ICC/IF

Anti-ACD mouse monoclonal antibody (TA504201) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACD(RC204381). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ACD Antibody in Immunocytochemistry (ICC/IF)
ACD Antibody in Western Blot (WB)
ACD Monoclonal Antibody (OTI1C8), TrueMAB™

Product Details

TA504201

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Immunocytochemistry (ICC/IF)

1:100
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

OTI1C8

Immunogen

Full length human recombinant protein of human ACD produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.72 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes a uridine 5' -monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5' -monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5' -monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Adrenocortical dysplasia protein homolog; POT1 and TIN2-interacting protein; TIN2 interacting protein 1; TPP 1; TPP I; TPPI

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Gene Aliases: ACD; PIP1; PTOP; TINT1; TPP1

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UniProt ID: (Human) Q96AP0

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Entrez Gene ID: (Human) 65057

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Function(s)
protein binding telomeric DNA binding macromolecular complex binding DNA polymerase binding
Process(es)
telomere maintenance skeletal system development urogenital system development intracellular protein transport telomere maintenance via telomerase telomere capping embryonic limb morphogenesis protection from non-homologous end joining at telomere telomere assembly negative regulation of telomere maintenance via telomerase positive regulation of telomere maintenance via telomerase segmentation positive regulation of telomerase activity positive regulation of single-stranded telomeric DNA binding protein localization to chromosome, telomeric region establishment of protein localization to telomere
It has to be done as per old AB suggested Products section.
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