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Invitrogen
ACAT2 Polyclonal Antibody
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Product Details
PA5-40598
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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RRID
Product Specific Information
Peptide sequence: SREDQDKVAV LSQNRTENAQ KAGHFDKEIV PVLVSTRKGL IEVKTDEFPR
Sequence homology: Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 100%
Target Information
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: acetoacetyl Coenzyme A thiolase; Acetyl-CoA acetyltransferase, cytosolic; Acetyl-CoA transferase-like protein; AE1; BND3; CD233; Cytosolic acetoacetyl-CoA thiolase; DI; EMPB3; EPB3; FR; RTA1A; SW; WD; WD1; WR
Gene Aliases: ACAT2; ACTL
UniProt ID: (Human) Q9BWD1
Entrez Gene ID: (Human) 39
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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