Invitrogen

ACADL Polyclonal Antibody

Name: ACADL Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-82450

Advanced Verification

View all (11) ACADL antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (5)
Advanced Verification (1)

ACADL Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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ACADL Antibody (PA5-82450) in IHC (P)

Immunohistochemical analysis of ACADL in human lung using ACADL Polyclonal Antibody (Product # PA5-82450) shows moderate to strong granular cytoplasmic positivity in macrophages.

Product Image Gallery

ACADL Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of ACADL demonstrates antibody specificity. Immunohistochemical analysis of ACADL using anti-ACADL Polyclonal Antibody (Product #PA5-82450), shows significant staining of ACADL in thyroid gland and shows minimal or weak staining in cerebral cortex tissues. The relative expression levels of ACADL within each tissue is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image ACADL Polyclonal Antibody

Product Details

PA5-82450

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ACADL. Recombinant protein control fragment (Product #RP-88960).

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.10 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2789608

Product Specific Information

Immunogen sequence: GEERLETPSA KKLTDIGIRR IFSPEHDIFR KSVRKFFQEE VIPHHSEWEK AGEVSREVWE KAGKQGLLGV NIAEHLGGIG GDLYSAAIVW EEQAYSNCSG PGFSIHSGIV MSYITNHGSE EQIKHFIPQM T

Target Information

The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: acetyl-Coenzyme A dehydrogenase, long-chain; Acyl Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long-chain; LCAD; LCAD long chain acyl-CoA dehydrogenase; long-chain acyl-CoA dehydrogenase; Long-chain specific acyl-CoA dehydrogenase, mitochondrial

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Gene Aliases: AA960361; ACAD4; ACADL; ACOADA; AU018452; C79855; LCAD

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UniProt ID: (Human) P28330, (Mouse) P51174, (Rat) P15650

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Entrez Gene ID: (Human) 33, (Mouse) 11363, (Rat) 25287

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Function(s)

fatty-acyl-CoA binding acyl-CoA dehydrogenase activity long-chain-acyl-CoA dehydrogenase activity electron carrier activity palmitoyl-CoA oxidase activity flavin adenine dinucleotide binding oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors

Process(es)

temperature homeostasis lipid metabolic process fatty acid metabolic process metabolic process carnitine metabolic process, CoA-linked fatty acid beta-oxidation using acyl-CoA dehydrogenase carnitine catabolic process long-chain fatty acid catabolic process cellular lipid catabolic process negative regulation of fatty acid biosynthetic process negative regulation of fatty acid oxidation protein homotetramerization oxidation-reduction process regulation of cholesterol metabolic process fatty acid beta-oxidation lipid homeostasis

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ACADL Polyclonal Antibody

ACADL Antibody (PA5-82450) in IHC (P)

Product Details

PA5-82450

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

References (0)

Bioinformatics

Performance Guarantee

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