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  • Primary Antibodies ›
  • ABCD1 Antibodies

Invitrogen

ABCD1 Polyclonal Antibody

View all (27) ABCD1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite ABCD1 Polyclonal Antibody

  • Antibody Testing Data (2)
ABCD1 Antibody in Immunocytochemistry (ICC/IF)
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ABCD1 Antibody in Immunocytochemistry (ICC/IF)
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ABCD1 Antibody (PA5-80291) in ICC/IF

Immunofluorescence staining of ABCD1 in MCF7 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with ABCD1 Polyclonal Antibody (Product # PA5-80291, 1:500) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to cytoplasm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ABCD1 Antibody in Immunocytochemistry (ICC/IF)
ABCD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Details

PA5-80291

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1,000
-

Immunocytochemistry (ICC/IF)

1:200-1:1,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to the center region of the Human ABCD1

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A, Antigen affinity chromatography

Storage buffer

PBS, pH 7

Contains

0.03% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2787622

Product Specific Information

This antibody has specificity for Human ABCD1.

Target Information

This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Adrenoleukodystrophy protein; ALDP; ATP-binding cassette sub-family D member 1; ATP-binding cassette, sub-family D (ALD), member 1

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Gene Aliases: ABC42; ABCD1; ALD; ALDP; AMN

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UniProt ID: (Human) P33897

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Entrez Gene ID: (Human) 215

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Function(s)
transporter activity long-chain fatty acid transporter activity peroxisomal fatty-acyl-CoA transporter activity protein binding ATP binding ATPase activity enzyme binding ATPase activity, coupled to transmembrane movement of substances identical protein binding protein homodimerization activity
Process(es)
fatty acid beta-oxidation peroxisome organization peroxisomal long-chain fatty acid import peroxisomal membrane transport fatty acid beta-oxidation using acyl-CoA oxidase alpha-linolenic acid metabolic process long-chain fatty acid catabolic process very long-chain fatty acid catabolic process linoleic acid metabolic process transmembrane transport
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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