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Invitrogen
ABCB4 Polyclonal Antibody
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FIGURE: 1 / 3
ABCB4 Antibody (PA5-100194) in ICC/IF
Product Details
PA5-100194
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
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Shipping conditions
RRID
Product Specific Information
Antibody detects endogenous levels of total MDR3.
Target Information
The membrane-associated protein encoded ABCB4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: ABC20; ATP-binding cassette sub-family B member 4; ATP-binding cassette, sub-family B (MDR/TAP), member 4; CD243; CLCS; GP170; MDR1; MGC163296; Multidrug resistance protein 2; Multidrug resistance protein 3; multiple drug resistance 3; P glycoprotein 2; P glycoprotein 3/multiple drug resistance 3; P-glycoprotein 2; P-glycoprotein 3; P-glycoprotein-3/multiple drug resistance-3; P-GP; PGY1; Phosphatidylcholine translocator ABCB4
Gene Aliases: ABC21; ABCB4; GBD1; ICP3; mdr-2; MDR2; MDR2/3; MDR3; PFIC-3; Pgy-2; Pgy2; PGY3
UniProt ID: (Human) P21439, (Mouse) P21440
Entrez Gene ID: (Human) 5244, (Mouse) 18670
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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