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Proteintech
14-3-3 Monoclonal Antibody (2E10A3)
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Product Details
66061-1-IG
Species Reactivity
Published species
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Product Specific Information
66061-1-Ig recognizes 14-3-3 tau (YWHAQ), eta (YWHAH), and zeta (YWHAZ), but not epsilon (YWHAE).
Immunogen sequence: MEKTELIQK AKLAEQAERY DDMATCMKAV TEQGAELSNE ERNLLSVAYK NVVGGRRSAW RVISSIEQKT DTSDKKLQLI KDYREKVESE LRSICTTVLE LLDKYLIANA TNPESKVFYL KMKGDYFRYL AEVACGDDRK QTIDNSQGAY QEAFDISKKE MQPTHPIRLG LALNFSVFYY EILNNPELAC TLAKTAFDEA IAELDTLNED SYKDSTLIMQ LLRDNLTLWT SDSAGEECDA AEGAEN (1-245 aa encoded by B C056867)
Target Information
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 14-3-3 protein T-cell; 14-3-3 protein tau; 14-3-3 protein theta; 14-3-3 tau; 14-3-3 theta; OTTHUMP00000165887; Protein HS1; protein tau; protein, theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Gene Aliases: 14-3-3; 14-3-3t; 1C5; 2700028P07Rik; AA409740; AU021156; HS1; R74690; YWHAQ
UniProt ID: (Human) P27348, (Rat) P68255, (Mouse) P68254
Entrez Gene ID: (Human) 10971, (Rat) 25577, (Mouse) 22630
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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