VPS26A Antibodies

Target Information

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

AA407240; FLJ12930; H beta 58; h58 protein; HB58; Hbeta58; Hbeta58 homolog; hVPS26; mVPS26; OTTHUMP00000019721; PEP8A; vacuolar protein sorting 26 homolog A; vacuolar protein sorting 26 homolog A (S. pombe); vacuolar protein sorting 26 homolog A (yeast); vacuolar protein sorting-associated protein 26A; vacuole protein sorting 26; vesicle protein sorting 26A; Vps26; VPS26 retromer complex comonent A; VPS26 retromer complex component A; VPS26, retromer complex component A; Vps26a