ADORA3 Antibodies

Target Information

Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response and the inhibition of protein synthesis The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthesis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNF alpha and blocks the endotoxin CD14 receptor signal transduction pathway.

Synonyms

A3AR; A3R; AA3R; AD026; adenosine A3 receptor; Adenosine A3-R; adenosine receptor A3; ADORA3; ARA3; BA552M11.5; Gpcr2; G-protein coupled receptor 2; RP11-552M11.7; Tgpcr1