STAT4 Antibodies

Antibodies that detect STAT4 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target STAT4 in Human, Mouse and Rat samples. Our STAT4 monoclonal, polyclonal and recombinant... Antibodies that detect STAT4 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target STAT4 in Human, Mouse and Rat samples. Our STAT4 monoclonal, polyclonal and recombinant monoclonal antibodies are... Antibodies that detect STAT4 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target STAT4 in Human, Mouse and Rat samples. Our STAT4 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Armenian Hamster. These antibodies have been verified by Cell treatment and Relative expression to confirm specificity to STAT4. Find the STAT4 antibody that fits your needs. Choose from 1 of 62 STAT4 antibodies, which have been validated in experiments with 35 publications and 197 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other... Antibodies that detect STAT4 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target STAT4 in Human, Mouse and Rat samples. Our STAT4 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Armenian Hamster. These antibodies have been verified by Cell treatment and Relative expression to confirm specificity to STAT4. Find the STAT4 antibody that fits your needs. Choose from 1 of 62 STAT4 antibodies, which have been validated in experiments with 35 publications and 197 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

STAT4 was originally identified using degenerate primers complementary to sequences encoding conserved regions of other STAT proteins. The STAT4 protein is most similar to STAT1 (52%) and STAT3 (47%). Functionally, STAT4 is similar to other STAT family members in that it can be tyrosine phosphorylated by Jak1 or Jak2. STAT4 forms homodimers and heterodimers with related STAT family members. Tyrosine phosphorylated STAT4 can bind the IFN-gamma activated site (GAS). Serine phosphorylation of STAT is also required for maximal transcriptional activity. STAT4 expression is restricted to the thymus, spleen and testis. Until recently the cytokine(s) responsible for activation of STAT4 had not been identified. STAT4 is now known to be activated by the cytokine interleukin 12 (IL-12). IL-12 is required for the T-cell independent induction of IFN-gamma which is a key step in the initial suppression of bacterial and parasitic infections. In addition, IL-12 is required for the development of a Th1 response which is necessary for effective host defense against intracellular pathogens. STAT4-deficient mice display impaired IL-12 development of Th1 cells and enhanced development of Th2 cells. A recent study in mouse has shown that in response to viral infection IFN-a/b activation of STAT4 is required for IFN-g production.

Synonyms

CIS4; HSPC060; OTTHUMP00000163553; Signal transducer and activator of transcription 4; SLEB11; SOCS4; SOCS6; SSI4; STAI4; STAT; Stat4; STATI4

Target Video

6320273991112

STAT4 antibodies from Thermo Fisher Scientific

https://cf-images.us-east-1.prod.boltdns.net/v1/static/3663210762001/6ed98fda-bd9e-4952-af70-c3cd5a897fbc/53d5d929-63b5-42f4-9634-47dba75177d4/160x90/match/image.jpg

Learn more about STAT4 primary antibodies that can be used in Western Blot, Immunohistochemistry, Immunocytochemistry and Flow Cytometry in Human, Mouse and Rat samples.

stat4

PT0M32S

2023-02-12T18:35:24.503Z

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STAT4 Antibodies

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