CD42b Antibodies

Antibodies that detect CD42b can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target CD42b in Human, Mouse, Porcine and Rat samples. Our CD42b monoclonal, polyclonal and... Antibodies that detect CD42b can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target CD42b in Human, Mouse, Porcine and Rat samples. Our CD42b monoclonal, polyclonal and recombinant monoclonal... Antibodies that detect CD42b can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target CD42b in Human, Mouse, Porcine and Rat samples. Our CD42b monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the CD42b antibody that fits your needs. Choose from 1 of 51 CD42b antibodies, which have been validated in experiments with 52 publications and 76 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody... Antibodies that detect CD42b can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, ELISA and Immunoprecipitation. These antibodies target CD42b in Human, Mouse, Porcine and Rat samples. Our CD42b monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the CD42b antibody that fits your needs. Choose from 1 of 51 CD42b antibodies, which have been validated in experiments with 52 publications and 76 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. CD42b expression and activation seems to be regulated by VEGF and PDGF. CD42b composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis. Further, CD42b antigen is expressed on platelets and on megakaryocytes in bone marrow. Several polymorphisms and mutations have been described in the CD42b, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease.

Synonyms

antigen CD42b-alpha; BDPLT1; BDPLT3; BSS; CD42a; CD42B; CD42b-alpha; DBPLT3; Glycocalicin; glycoprotein 1b, alpha polypeptide; glycoprotein Ib (platelet), alpha polypeptide; glycoprotein Ib platelet alpha subunit; glycoprotein Ib platelet subunit alpha; glycoprotein Ibalpha; GP1B; GP1BA; GPIB; GPIb alpha; GP-Ib alpha; GPIbA; GPIbalpha; GPIX; GP-IX; MGC34595; mutant platelet membrane glycoprotein Ib-alpha; Platelet glycoprotein Ib alpha chain; platelet glycoprotein Ib alpha polypeptide; Platelet GPIX; platelet membrane glycoprotein 1b-alpha subunit; platelet membrane glycoprotein Ib-alpha; VWDP

Target Video

6320248717112

CD42b antibodies from Thermo Fisher Scientific

https://cf-images.us-east-1.prod.boltdns.net/v1/static/3663210762001/15bbeefb-930f-4bb5-acef-41b9aeec27fc/8ecfa928-c33e-47e7-ba63-a1cde2fa546b/160x90/match/image.jpg

Learn more about CD42b primary antibodies that can be used in Flow Cytometry, Western Blot, Immunohistochemistry and ELISA in Human, Mouse, Pig and Rat samples.

cd42b

PT0M32S

2023-02-12T11:50:47.527Z

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CD42b Antibodies

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