CD1c Antibodies

Antibodies that detect CD1c can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target CD1c in Human, Canine and Mouse samples. Our CD1c monoclonal and polyclonal antibodies are... Antibodies that detect CD1c can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target CD1c in Human, Canine and Mouse samples. Our CD1c monoclonal and polyclonal antibodies are developed in Mouse... Antibodies that detect CD1c can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target CD1c in Human, Canine and Mouse samples. Our CD1c monoclonal and polyclonal antibodies are developed in Mouse and Rabbit. Find the CD1c antibody that fits your needs. Choose from 1 of 67 CD1c antibodies, which have been validated in experiments with 26 publications and 192 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot... Antibodies that detect CD1c can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target CD1c in Human, Canine and Mouse samples. Our CD1c monoclonal and polyclonal antibodies are developed in Mouse and Rabbit. Find the CD1c antibody that fits your needs. Choose from 1 of 67 CD1c antibodies, which have been validated in experiments with 26 publications and 192 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

CD1c is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. This family of proteins is involved in the presentation of lipid and glycolipid antigens, both of self and microbial origin, to T cells during the adaptive immune response. CD1c is expressed on some circulating and marginal zone B cells, as well as in lymph nodes and germinal centers. It plays a crucial role in presenting lipid antigens, such as microbial fatty acids, to effector T cells. The protein encoded by the CD1c gene localizes to late endosomes and lysosomes, utilizing a tyrosine-based motif in its cytoplasmic tail for targeting. Vesicular acidification is required for CD1c to bind lipid antigens effectively. The human genome contains five CD1 family genes organized in a cluster on chromosome 1, with each member differing in cellular localization and specificity for particular lipid ligands. CD1c undergoes alternative splicing, resulting in three different isoforms: soluble, membrane-bound, and cytoplasmic/soluble isoforms, highlighting its functional diversity in immune processes.

Synonyms

BDCA1; CD1; CD1A; CD1c; CD1C antigen, c polypeptide; CD1c molecule; cortical thymocyte antigen CD1C; differentiation antigen CD1-alpha-3; R7; RP11-101J8.3; T-cell surface glycoprotein CD1c

Target Video

6320248992112

CD1c antibodies from Thermo Fisher Scientific

https://cf-images.us-east-1.prod.boltdns.net/v1/static/3663210762001/0798f034-b042-49b1-ac48-d4058c6b84e2/3d7be9e4-8a26-40e3-abaa-c2281f4cfcee/160x90/match/image.jpg

Learn more about CD1c primary antibodies that can be used in Flow Cytometry, Western Blot, Immunocytochemistry and Immunohistochemistry in Human, Dog and Mouse samples.

cd1c

PT0M39S

2023-02-12T11:47:51.277Z

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CD1c Antibodies

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